BMPR1a and BMPR1b Signaling Exert Opposing Effects on Gliosis after Spinal Cord Injury
نویسندگان
چکیده
منابع مشابه
BMPR1a and BMPR1b signaling exert opposing effects on gliosis after spinal cord injury.
Astrogliosis following spinal cord injury (SCI) involves an early hypertrophic response that is beneficial and a subsequent formation of a dense scar. We investigated the role of bone morphogenetic protein (BMP) signaling in gliosis after SCI and find that BMPR1a and BMPR1b signaling exerts opposing effects on hypertrophy. Conditional ablation of BMPR1a from glial fibrillary acidic protein (GFA...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2010
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.4459-09.2010